Restore Gold is rapidly gaining in popularity for its potential to treat Parkinson’s disease related symptoms. It has increasingly swept the market off its feet by containing seven very specific compounds in one capsule. For decades researchers have focused on compounds to help reduce Parkinson’s symptoms in patients. However, Restore Gold has done one better and brought all the seven much needed natural ingredients together to help potentially reduce Parkinson’s symptoms in its sufferers.

Ingredients

Tauroursodeoxycholic acid (TUDCA)

In recent years scientists have done a lot of research on different compounds and elements in order to understand their roles with regards to Parkinson’s. A groundbreaking discovery was made in 2013 proving that there is a compound called UDCA which helps restore mitochondrial functions in those suffering from Parkinson’s. When UDCA passes through the liver it combines with Taurine and becomes the famous TUDCA. Accumulating evidence suggests that mitochondrial dysfunction play a central role in Parkinson’s disease (PD). This evidence is based on the identification of PD-associated mutations in genes that affect mitochondrial function.TUDCA is an anti-apoptotic molecule shown to interfere with the mitochondrial pathway of cell death. Importantly, TUDCA was demonstrated to protect against MPTP-induced neurodegeneration in mice, but the mechanisms involved are still unknown [1].

TUDCA is also used in liver restore supplements and has liver regeneration properties. We believe TUDCA to be one of the most important ingredients in our Restore Gold supplements and added 350mg in each capsule. The TUDCA present in these supplements may potentially help restore mitochondrial function and may prevent depletion of dopamine producing cells in our nervous system.

L-Tyrosine

N-acetyl-cysteine (NAC)

N-acetyl-cysteine is one of the best antioxidant compounds which may help improve dopamine transporter (DAT) binding in people with Parkinson’s. It is one of the seven key ingredients of our Restore Gold capsules, and each capsule contains 410 mg of NAC. NAC may also help produce glutathione naturally in the brain as Parkinson’s causes a deficiency of glutathione. A recent study stated that NAC may positively affect the dopaminergic system in patients with PD, with corresponding positive clinical effects [4]. This is an exciting study that suggests a natural molecule such as NAC can potentially help improve dopamine function and symptoms in Parkinson’s patients. Many other studies are slowly proving NAC to be a key ingredient to warrant further research in managing and reducing the symptoms of Parkinson’s Disease.

Green Tea Leaf

Green Tea Extract is one of the most famous and popular compounds correlated with a decrease in memory loss or dementia. Researchers believe it too have positive effects on people with Parkinson’s. Green Tea has antioxidant properties and it contains polyphenols which may protect humans against age related issues. Epigallocatechin gallate (EGCG) is known to penetrate brain tissues and protect the brain in Parkinson’s disease. It is one of the main compounds found in Green Tea Extract. Numerous studies proved that the EGCG present in Green tea had anti-inflammatory properties and may prevent the loss of dopaminergic cells in Parkinson’s patients. Green tea may also help in reducing COMT, the dopamine killing enzymes in Parkinson’s patients. This may help sustain dopamine levels and as such slow down the disease from spreading. Restore Gold capitalise on green tea’s neuro protective effects and include 220mg Green Tea Leaf in each capsule.

Grape Seed Extract

Grape Seed Extract is known to potentially enhance mitochondrial function in Parkinson’s patients. It also allows the brain to remove toxic aggregates from it hence improving the immunity of the nervous system. A recent study showed that besides polyphenols, grape skin and seeds also contain anti-oxidative components, including proanthocyanidin and quercetin, which may actively contribute to protecting against oxidative stress and mediated tissue injury [5].

Oxidative stress is an imbalance between the production of free radicals and the ability of cells to detoxify them. These free radicals, or reactive oxygen species, are harmful to the cells and are associated with a number of diseases, including Parkinson’s disease.Grape seed extract in Restore Gold may help ease symptoms of PD by improving mitochondrial function and reducing oxidative stress.

Acetyl L-Carnitine

Carnitine, produced by the kidneys and liver is a molecule present in most cells of the body, which helps carry long chain fatty acids through the mitochondrial membrane where they are oxidized. Studies suggest that the supplement Acetyl l-carnitine can potentially reduce the onset of Parkinsons caused by mitochondrial dysfunction and oxidative damage.

Researchers have proved carnitine to be a neuroprotectant as it protects cells from mitochondrial dysfunction, oxidative stress and aggregation of alpha-synuclein proteins. An adequate dose of mitochondrial nutrients may play a major role in preventing the onset of Parkinson’s disease related symptoms. Due to which we have added 110mg of Acetyl L-Carnitine in our Restore Gold Capsules.

Alpha Lipoic Acid (ALA)

Alpha lipoic acid is an antioxidant that is naturally produced within the body. It may have many therapeutic benefits from reducing inflammation to fighting oxidation in the body. It may also help in protecting liver function and reducing memory loss and cognition. According to research it may potentially help in producing cellular energy and reducing toxins and free radicals in the brain by blistering levels of glutathione and vitamin E. We have added 110mg of ALA in our Restore Gold capsules to help deliver neuroprotectants to the nervous system to potentially aid in the relief of Parkinson’s related symptoms.

Zinc

A lot of research has been done on zinc with regards to neurobiology and its potential benefits in it. Studies have shown it may play a role in the pathogenesis of neurodegenerative diseases such as Parkinson’s disease. Parkinson’s occurs by the loss of dopamine producing cells in the nervous system. The enzyme, superoxide dismutase (SODCu2Zn2), is found in high concentrations in the substantia nigra where it protects dopamine making neurons. The 50mg Zinc present in our supplement may help to increase SODCu2Zn2. Studies have proved the requirement of Zinc for many neuro functions including the protection of dopamine inducing neurons.